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Speakers

Keynote and invited speakers

Researchers working across the mechanisms of alternative DNA structure formation, genome stability, and the genome-scale mapping of structure-forming sequences. Additional invited speakers will be announced as invitations are confirmed.


The University of Texas at Austin

Portrait of Karen M. Vasquez

Keynote speaker

Karen M. Vasquez, PhD

Professor and Division Head, Pharmacology and Toxicology · Jaime N. Delgado Endowed Chair

College of Pharmacy and Dell Pediatric Research Institute, The University of Texas at Austin

Keynote title to be announced.

Karen M. Vasquez is Professor and Head of the Division of Pharmacology and Toxicology in the College of Pharmacy at The University of Texas at Austin, where she holds the Jaime N. Delgado Endowed Chair and is based at the Dell Pediatric Research Institute. Her research addresses alternative DNA structures, DNA repair and genome stability, mutagenesis, and the mechanisms that connect DNA structure to disease. She is the organizer of this meeting and its keynote speaker.

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Portrait of Kateryna D. Makova

Keynote speaker

Kateryna D. Makova, PhD

Verne M. Willaman Chair in Life Sciences · Professor of Biology

Penn State University

Keynote title to be announced.

Kateryna D. Makova is a Professor of Biology at Penn State University whose laboratory focuses on evolutionary and medical genomics. Her research investigates the mechanisms driving genomic variation and evolution, with a primary emphasis on non-B DNA structures, sex chromosome evolution, mitochondrial DNA mutation dynamics, and the genomic drivers of disease susceptibility and complex traits.

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Portrait of Sergei M. Mirkin

Keynote speaker

Sergei M. Mirkin, PhD

White Family Chair in Biology · Professor of Biology

Tufts University

Keynote title to be announced.

Sergei M. Mirkin is a Professor of Biology at Tufts University and a pioneer in the study of non-canonical DNA structures. His laboratory investigates the mechanisms of genome instability triggered by structure-prone repetitive DNA sequence motifs, exploring how triplet repeat expansions, non-B DNA formations, and replication-transcription collisions drive genetic disease and mutagenesis.

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Portrait of Catherine Freudenreich

Keynote speaker

Catherine Freudenreich, PhD

Professor and Chair, Department of Biology

Tufts University

Keynote title to be announced.

Catherine Freudenreich is a Professor and Chair of the Department of Biology at Tufts University. Her research program centers on chromosome fragility, DNA repair, and genome stability, focusing specifically on how structure-forming repetitive DNA sequences impede DNA replication forks, trigger chromosomal breakages, and induce repeat expansion mutations associated with neurodegenerative disorders.

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Invited speakers

Invitations are still going out. This roster grows as speakers accept and confirm their talk titles — no one is listed here before they have agreed to speak.

  • Portrait of Ilias Georgakopoulos-Soares

    Ilias Georgakopoulos-Soares, PhD

    Assistant Professor

    The University of Texas at Austin

    Talk title to be announced.

    Session III — Mapping and Modeling Alternative DNA Structures Across Genomes

    Biography

    Ilias Georgakopoulos-Soares is an Assistant Professor at The University of Texas at Austin whose research integrates computational biology, bioinformatics, genomics, and machine learning. His work spans genome-scale detection of structure-forming sequences, comparative and population genomics, and the analysis of variation, instability, and evolutionary constraint across reference genomes, pangenomes, and cancer genomes.

  • Portrait of Marco Di Antonio

    Marco Di Antonio, PhD

    Associate Professor in Chemical Biology

    Department of Chemistry, Imperial College London

    Talk title to be announced.

    Biography

    Marco Di Antonio is an Associate Professor in Chemical Biology in the Department of Chemistry at Imperial College London, a BBSRC David Phillips Fellow, and a Fellow of the Lister Institute of Preventive Medicine. His research uses organic chemistry to design small-molecule probes that interrogate DNA secondary structures, including G-quadruplexes, and their roles in ageing and cancer biology, building on earlier work demonstrating G-quadruplex DNA and RNA structures in human cells and mapping them genome-wide.

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  • Portrait of David Rusling

    David Rusling, PhD

    Associate Professor in Bioengineering

    School of Medicine, Pharmacy and Biomedical Sciences, University of Portsmouth

    Talk title to be announced.

    Biography

    David Rusling is an Associate Professor in Bioengineering in the School of Medicine, Pharmacy and Biomedical Sciences at the University of Portsmouth. His research centers on engineering nucleic acid-based platforms for biotechnology and healthcare, spanning DNA recognition, triplex-forming oligonucleotides, DNA origami, and nanostructures, with applications in precision gene targeting, synthetic biology, and therapeutic discovery.

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  • Portrait of Nayun Kim

    Nayun Kim, PhD

    Associate Professor of Pharmacology and Toxicology

    College of Pharmacy, The University of Texas at Austin

    Talk title to be announced.

    Biography

    Nayun Kim is an Associate Professor of Pharmacology and Toxicology in the College of Pharmacy at The University of Texas at Austin. Her laboratory investigates genome instability mechanisms centered on G-quadruplex DNA, including proteins and topoisomerase activity that suppress G-quadruplex formation, zinc-finger proteins that interact with these structures, and their role in mitochondrial genome maintenance.

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  • Portrait of Amy M. Whitaker

    Amy M. Whitaker, PhD

    Assistant Professor

    Molecular Therapeutics Program and Cancer Epigenetics Institute, Fox Chase Cancer Center

    Talk title to be announced.

    Biography

    Amy M. Whitaker is an Assistant Professor in the Molecular Therapeutics Program and a member of the Cancer Epigenetics Institute at Fox Chase Cancer Center. Her laboratory investigates oxidative DNA damage within G-quadruplex-forming sequences and how its repair couples to the transcriptional regulation of key tumor suppressors and oncogenes, using structural biology, nucleic acid enzymology, single-molecule fluorescence microscopy, and cell-based assays to identify molecular targets for cancer therapy.

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  • Portrait of Quentin Vicens

    Quentin Vicens, ScD

    Assistant Professor

    Department of Biology and Biochemistry, University of Houston

    Talk title to be announced.

    Biography

    Quentin Vicens is an Assistant Professor in the Department of Biology and Biochemistry at the University of Houston. His lab works at the intersection of computational and experimental biology, examining interactions between non-canonical RNA structures — including Z-RNA — and host immune proteins, and developing open-source database tools, benchmarks, algorithms, and language models to advance predictions of RNA structure.

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Additional invited speakers will be announced as invitations are confirmed.

Be notified as additional speakers and sessions are confirmed.